A new American study provided evidence that shows how immune responses can cause chronic inflammation and contribute to the continuous symptoms of chronic fatigue syndrome, which paves the way for new therapeutic ways to confront the symptoms of this syndrome and other post-infection syndromes, such as the long-term coffee-19 syndrome.
Patients with chronic fatigue syndrome show increasing immune responses to bacteria, viruses and fungi, and despite the importance of these responses in infection control, their excessive activity can cause damage if it does not eras.
The study was conducted by researchers from the Infection and Immunology Center at the Milman College of Public Health at the University of Colombia, in the United States, in cooperation with a team of several pioneering researchers in the field of chronic fatigue syndrome/encephalitis and muscle marrow. Its results were published in the Metabolic Health and Disease, and Yurrick Alert wrote about it.
Chronic fatigue syndrome is an exhausted disorder that lasts for at least 6 months, and it is characterized by a feeling of unjustified fatigue, the occurrence of thorns and exhaustion after making physical effort, in addition to poor perception, and the inability of constant standing, as many patients indicate the presence of muscle pain and an imbalance in the digestive system.
Chronic fatigue syndrome affects millions of people around the world, and is more common in male females. The causes of chronic fatigue syndrome did not explain; However, it was previously described as a psychological disorder, but abundant evidence of blood, muscles and brain studies have been classified as physical syndrome and increasingly and fulfilled as a biological disorder whose essence is the disruption of immunity regulation.
Most patients suffer from flu -like symptoms before developing chronic fatigue syndrome. The researchers assumed that this condition is caused by an abnormal immune response to the infection, which leads to cellulitis, damage and metabolic disorders. The overlapping symptoms of chronic fatigue syndrome and long coffee-19 syndrome confirms that infection may cause this syndrome.
In the context of the new study, the research team conducted a comprehensive analysis of blood samples of 56 patients with chronic fatigue syndrome, along with 52 sound people from a control group, chosen from various geographical areas, including New York and California from the United States.
The researchers drew a map of both metabolom (cell metabolism products) and protein (proteins produced through biological processes) using the latest technology.
They simulated infection through microbial stimuli, and monitored the responses of immune cells, which allowed an unprecedented vision of functional imbalance in the immune paths associated with chronic fatigue syndrome.
The results also revealed that there are disturbances in the interconnected biological processes, which are usually noted in chronic inflammatory cases, and indicate a state of imbalance in metabolism, immune disorder, and tissue damage, which may stimulate an inflammatory response at the level of the organs in the body. Understanding these relationships is very important to develop treatment strategies targeting multiple aspects of the disease.