Pymrighs magazine stated that researchers are developing small biologically modified capsules to reduce encephalitis without rejecting them.
Although inflammation may sometimes be useful in some cases, including promoting wound healing, brain inflammation is related to disease such as Alzheimer’s and Parkinson.
A team of biological researchers and neurologists succeeded in developing soft, gel -like capsules, almost the size of a grain of sand that can surround human brain cells called stellar cells and can be implanted in the brain.
The capsules aim to push the cells inside them to secrete an anti-inflammatory protein called Interleukin-1 anti-Inter-1 to the surrounding environment, and thus significantly reduce inflammatory responses in tests with test tubes and mice brains.
“Given the capsules will form a material barrier between the cultivated stellar cells and the brain tissue, it is expected that (stellar cells) anti -inflammatory proteins while avoiding immune rejection and unwanted deployment in the brain,” said study commander Robert Krensic of the Houston Methodist Research Institute in the United States.
“Cell packaging in a way that protects them from (refusal) immunity was a major challenge in this field,” said Omid Vesier, from the University of Rice in the United States, another leader who participated in the study.
“We hope this work will help bring cell therapy to become a real therapeutic option for patients with degenerative neurological diseases,” Omid Vesier added.