Australian researchers- in a study of the first of its kind- found that ibuprofen and Paracetamol enhance the resistance of antibiotics when using them individually, and exacerbate them when they are used together.
The study was conducted by researchers from the University of Southern Australia, and its results were published in the “NB Jay” magazine for microbial and resistance anti -resistance on August 25, and the “Yorik Alrt” website was written about.
Researchers have offered coli -coli bacteria – which are common and caused bowel infections and urinary tract – for cyberboxacin with ibuprofen and Paracetamol, and Seroprofloxacin is a broad -spectrum antibiotic.
The bacteria that were exposed to these medications together developed more genetic mutations compared to the bacteria that were exposed to the antibiotic alone, which helped them grow faster and gain high resistance. It is concerned that the bacteria were not only resistant to the antibiotic ciprofloxacin, but an increase in its resistance to many other antibiotics was also observed from different categories.
“The antibiotics have always been important in treating infectious diseases, but their widespread misuse has led to a global increase in antibiotic -resistant bacteria,” says the researcher participating in the study.
“We discovered the genetic mechanisms behind this resistance, as Eboprofen and Paracetamol are activated bacteria to expel antibiotics and reduce their effectiveness,” she added.
The study was evaluated 9 commonly used drugs: ibuprofen (anti -inflammatory pain reliever), diclofenac (anti -inflammatory pain reliever), paracetamol (pain reliever and antipyretic), Furoseimide (diuretic), metformin (for high blood sugar levels associated with diabetes), Aturvastatin (to help lower cholesterol Blood fats), tramadol (stronger pain after surgery), Timazepam (to treat sleep problems), Sudovidrine (congestion).
“The antibiotic resistance is no longer limited to antibiotics only,” said Dr. Rieti. Combine two medications. “
The researchers call for more studies on drug reactions for anyone who follows long -term drug treatment systems, so that we can raise awareness of how common drugs affect the effectiveness of antibiotics.