American researchers said in a study that the alternatives to common pain relievers that do not require a prescription may one day be able to control pain without curbing inflammation that may be useful.
The study may lead to changes in the method of installing pain relievers.
Non -steroidal anti -inflammatory, which includes aspirin and ibuprofen, is among the most common pain relievers in the world. It prevents enzymes that produce prostaglandin, which works with the immune system to enhance inflammation by expanding blood vessels, increasing blood flow and attracting white blood cells to the location of the injury.
Prostaglands also alerts nerve endings, making them more responsive to pain signals.
Scientists generally believe that preventing or limiting inflammation is what treats pain. But inflammation, which is the response of the immune system to infection or infection, is sometimes useful and its inhibition can delay recovery and recovery from pain.
According to the journal Nature Communichens, researchers have now found that a protein is appointed on the surface of the prostaglandin, which is the EB2 future, responsible for causing pain, not inflammation.
They discovered that giving medicines to silence the EB2 receptors only removed the pain responses in mice without affecting the inflammation. “The inflammation can be beneficial to you, as it works and restores the natural function,” said the author of the study, Pierre Angelo, from the New York University Pain Research Center, in a statement.
Researchers said they are exploring whether it is possible to use drugs targeting EB2 receptors to treat pain in cases such as arthritis, which is usually treated with non -steroidal anti -inflammatory.