A recent study found that cats affected by dementia suffer from brain changes similar to those that Alzheimer’s patients suffer from humans, which provides a standard model to study this condition and used it to develop human treatments.
Scientists have discovered an accumulation of the bita -toxic amyloid protein in the brains of cats infected with this condition, which is one of the distinctive features of Alzheimer’s disease in humans.
Experts say that these results provide a clearer picture of how the amyloid beta causes a cerebral dysfunction and a memory loss linked to cats in cats.
Alzheimer’s disease is the most common causes of dementia, and this means that dementia and Alzheimer are not one thing. Decoration is a group of symptoms that may be caused by Alzheimer’s, as it may result from other disorders.
The study was conducted by researchers from the Center for Brain Science at the University of Edinburgh in the United Kingdom, and its results were published in the European Journal of Neuroscience on August 11, and wrote about it.
Many old cats are developing dementia, which leads to behavioral changes such as increasing the vocal tone (or inauguration), confusion and sleep disturbance, which are symptoms similar to those that are noticed in Alzheimer’s patients.
Professor Daniel Gan Moore, head of the Cats Medicine Department at the Royal College of Dick Veterinary Studies, said, “Defending in cats causes severe pain for them and their owner, and through conducting such studies we will be able to understand the best ways to treat them, this will be very useful for cats and their owners and people with Alzheimer’s disease and their loved ones, and the sheep in cats are an ideal natural model for Alzheimer’s disease,” said Professor Daniel Gan Moore, Head of Cat Medicine Department at the Royal Dick College for Veterinary Studies.
Tissue trim
Scientists at Edinburgh University examined the brains of 25 cats of different ages after her death, including cats showing signs of dementia.
Micro -microscopic images revealed the accumulation of the amyloid beta protein inside the nerve clamps, which are the bonds between the brain cells, in elderly cats and cats with dementia.
The nerve clamps allow messages to flow between the brain cells, which are vital for proper brain functions, and their loss strongly indicates a decrease in memory and thinking capabilities in humans with Alzheimer’s disease.
The research team also found evidence that stellar cells and small glial cells, which are types of support cells in the brain, swallowed up or ate the damaged neurons.
This process is known as “neurotransmitter trim”, which is important during brain growth, but it may contribute to the loss of nerve clamps in dementia patients.
Experts say that these results will not only help understand and manage dementia in cats, but also may also contribute – given the similarities between them – to develop future treatments for people with Alzheimer’s disease.
Scientists who study Alzheimer’s disease in the past have relied heavily on genetically modified rodent models, as rodents do not naturally develop dementia, and experts say that studying cats with dementia allows the possibility of developing knowledge and helping to develop treatments for both cats and humans.