A study revealed that the imbalance in the bacteria of the intestine leads to a disorder in the manufacture of neurotransmitters, which is reflected in the behavior of children with autism spectrum disorder.
The study was conducted by researchers from the University of Southern California in the United States, and published on Nature Communications on April 14, and wrote the Yorik Alrt.
The study showed how the turmoil in the bacteria of the intestine can lead to a defect in the metabolic products in the digestive system. This imbalance affects the production of neurotransmitters, specifically Serotonin, which is reflected in the behavior of children with autism.
Autism and digestive problems
“We know that children with autism have differences in brain function, some parts of their brains are either less active or more active compared to children with normal growth. We also know that they often suffer from problems in the digestive system, such as constipation, stomach pain and other digestive problems. This, autism is associated with various symptoms, including repeated behaviors and social difficulties. “
In this study, the researchers collected behavioral data and brain pictures of 43 children with autism and 41 children and compared them. In addition to collecting stool samples from the participants to analyze metabolic products (signs) produced by intestinal bacteria.
Dr. Lisa said that previous studies showed a difference in the bacterial environment in the intestine and the presence of a difference in the form of the brain in autistic patients, but this study came to link the relationship between them.
Children and serotonin behavior
The researchers linked these sides to the noticeable brain differences in children with autism and their behavioral characteristics. They focused on the path in which tryptophan decomposes to several receptors, including serotonin. Trobetovan amino acid is found in many foods.
Serotonin is one of the most important neurotransmitters in the body and is responsible for social reactions, such as treating emotions, learning and other functions. Because the intestine is one of the most important organs that produce serotonin, any change in bowel health may be reflected in its production.