A research team has discovered that the body is preparing itself early for the possibility of exacerbation of the disease even in simple cases of infection. Scientists have shown that with the beginning of a mild disease, the body produces special immune cells that were not previously known only in cases of severe chronic infection and tumors.
The study was conducted by researchers from Technical University of Munich and the Helmsuliz Munich Institute in Germany and published its results in the “Nature” magazine on April 7, and wrote about Yurrick Alrt.
T cells and their activities
There are different types of T cells in the body, each of which has a decisive role in the immune system. It fights pathogens and controls the immune response, but some sub -species become less effective or even completely stops with the progress of the disease, and this has negative results in certain and positive conditions in other cases.
The cells have a positive role in protecting the body. In continuous infection cases, the immune system may harm the body if it continues to fight the causes of diseases strongly. On the other hand, the exhaustion of T cells is a problem in treating cancer, as the treatments may not be effective.
“We have been able to prove that the body prepares sub -types of T cells to exhaust even in the early stages of infection for medium diseases,” says Datetar Zain, a professor of animal and immunity physiology at Munich Technical University and one of the authors participating in the study.
The body places the immune cells at its disposal
The team concluded from this discovery that the body collects a group of different T -cells early in the beginning of the disease to arm itself, to meet the different stages of the disease. Thus, the body has cells at its disposal to make the immune response more aggressive or more kindly based on the course of the disease.
“Our results are expanding the traditional idea about the development of T -cell exhaustion. Therefore, we assume that our observations will help understand the mechanisms behind the exhaustion of T cell deeper.”
To better understand these operations, it may contribute in the future to controlling the immune response, such as strengthening the immune system in cancer patients or weakening excessive defenses, as is common in severe cases of Covey-19.