A recent study revealed major differences in genetic expression in the fatty tissues that occur when a high -fat diet, calories and another low -fat system.
The genetic expression is the process through which the encrypted information in the gene is converted into a product that has a function. The researchers have identified 4 genes related to metabolism, calcium treatment and inflammation that may be possible therapeutic targets.
The study was conducted by researchers from Dilayer University in the United States, and its results were published in the Physiology Genomics, written on the Yurik Alert.
The research aimed to address the issue of obesity by researching it at the level of genes. The researchers discovered major differences in genetic expression in the fatty tissues. The fatty tissue was previously considered a fat store, and now it is known as an Endocrine Organ. The defect in the fatty tissue is associated with serious cardiovascular disease and metabolism.
How does the diet affect the fatty tissue?
The researchers examined how the diet affects the genetic expression in the fatty tissues using two groups of laboratory mice. One of the two groups eaten a diet that resembles a western diet, high -fat and calories, while the other group ate normal food for more than a year.
“We expected to see major fat changes,” said Abra, and the assistant professor in action and applied physiology at the College of Health Sciences at Dilayer University. Bad and obesity. “
The study found that more than 300 gene was expressed differently in subcutaneous adipose tissue, a less dangerous form of fat. In comparison, approximately 700 genes are expressed different in Vision Adipose Tissue. Violent fats or fats around vital organs increase the risk of a person with major health problems.
Among the thousands of genes that have been analyzed, the research has identified 4 genes linked to metabolism, calcium treatment and infections that deserve more research.
“We are already looking to see if these genes deserve to seek to improve the function of oily tissue in obesity. They can be targeted with existing drugs or producing new treatments specifically designed to influence these genes,” Vanch published.